Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: JUP All Species: 43.94
Human Site: T463 Identified Species: 87.88
UniProt: P14923 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P14923 NP_002221.1 745 81745 T463 V C A L R H L T S R H P E A E
Chimpanzee Pan troglodytes XP_001137676 774 84747 T465 I C A L R H L T S R H Q E A E
Rhesus Macaque Macaca mulatta XP_001107394 745 81756 T463 V C A L R H L T S R H P E A E
Dog Lupus familis XP_850439 744 81740 T462 V C A L R H L T S R H P E A E
Cat Felis silvestris
Mouse Mus musculus Q02257 745 81782 T463 V C A L R H L T S R H P E A E
Rat Rattus norvegicus Q6P0K8 745 81782 T463 V C A L R H L T S R H P E A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516985 781 85506 T472 I C A L R H L T S R H Q E A E
Chicken Gallus gallus NP_990412 781 85420 T472 I C A L R H L T S R H Q E A E
Frog Xenopus laevis P30998 738 81693 T459 V C A M R H L T S R H Q D A E
Zebra Danio Brachydanio rerio XP_002665522 722 79064 T445 V C A L R H L T S R H P D A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18824 843 91134 T480 V C A L R H L T S R H V D S E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O44326 678 74493 V435 L E T L R T P V I K A A L G V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.8 99.8 98.9 N.A. 98.3 97.9 N.A. 66.5 66.3 81.2 70.5 N.A. 56.8 N.A. 28.7 N.A.
Protein Similarity: 100 77.7 99.8 99.3 N.A. 99.3 99 N.A. 77.3 77 90.3 81.8 N.A. 69.1 N.A. 46.9 N.A.
P-Site Identity: 100 86.6 100 100 N.A. 100 100 N.A. 86.6 86.6 80 93.3 N.A. 80 N.A. 13.3 N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. 93.3 93.3 93.3 100 N.A. 93.3 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 92 0 0 0 0 0 0 0 9 9 0 84 0 % A
% Cys: 0 92 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 % D
% Glu: 0 9 0 0 0 0 0 0 0 0 0 0 67 0 92 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % G
% His: 0 0 0 0 0 92 0 0 0 0 92 0 0 0 0 % H
% Ile: 25 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % K
% Leu: 9 0 0 92 0 0 92 0 0 0 0 0 9 0 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 9 0 0 0 0 50 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 34 0 0 0 % Q
% Arg: 0 0 0 0 100 0 0 0 0 92 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 92 0 0 0 0 9 0 % S
% Thr: 0 0 9 0 0 9 0 92 0 0 0 0 0 0 0 % T
% Val: 67 0 0 0 0 0 0 9 0 0 0 9 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _